The Effect of Chromosome 9p21 Variants on Cardiovascular Disease May Be Modified by Dietary Intake
نویسندگان
چکیده
منابع مشابه
The effect of chromosome 9p21 variants on cardiovascular disease may be modified by dietary intake.
1. Do R, Xie C, Zhang X, Männistö S, Harald K, Islam S, Bailey SD, Rangarajan S, McQueen MJ, Diaz R, Lisheng L, Wang X, Silander K, Peltonen L, Yusuf S, Salomaa V, Engert JC, Anand SS; INTERHEART Investigators. The effect of chromosome 9p21 variants on cardiovascular disease may be modified by dietary intake: evidence from a case/control and a prospective study. PLoS Med. 2011;8:e1001106. 2. Ll...
متن کاملThe Effect of Chromosome 9p21 Variants on Cardiovascular Disease May Be Modified by Dietary Intake: Evidence from a Case/Control and a Prospective Study
BACKGROUND One of the most robust genetic associations for cardiovascular disease (CVD) is the Chromosome 9p21 region. However, the interaction of this locus with environmental factors has not been extensively explored. We investigated the association of 9p21 with myocardial infarction (MI) in individuals of different ethnicities, and tested for an interaction with environmental factors. METH...
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AIMS Genetic predisposition for cardiovascular disease (CVD) is likely to be modified by environmental exposures. We tested if the associated risk of CVD and CVD-mortality by the single nucleotide polymorphism rs4977574 on chromosome 9p21 is modified by life-style factors. METHODS AND RESULTS A total of 24,944 middle-aged subjects (62% females) from the population-based Malmö-Diet-and-Cancer-...
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ژورنال
عنوان ژورنال: Circulation: Cardiovascular Genetics
سال: 2012
ISSN: 1942-325X,1942-3268
DOI: 10.1161/circgenetics.111.962662